Persisting Pandemics was authored by Powel H. Kazanjian, MD, PhD, a professor emeritus at the University of Michigan Medical School and School of Public Health. The book explores the history of syphilis and AIDS to provide insights into the limits of biomedicine and our experience with epidemics today. The need for a public health approach to address mistrust in science, government indifference, and racial inequalities is relevant for strategies to eliminate COVID-19 today.